Substitutes for Morphine and Heroin

Micro-Crystal Identification Tests for Morphine, Heroin, Dilaudid, and Cocaine

Hair morphine concentrations of fatal heroin overdose cases and living heroin users.

AIMS To compare heroin and other opiate use of heroin overdose fatalities, current street heroin users and drug-free therapeutic community clients. DESIGN Hair morphine concentrations that assess heroin use and other opiate use in the 2 months preceding interview or death were compared between heroin overdose fatalities diagnosed by forensic pathologists (FOD) (n = 42), current street heroin ...

Concentrations of heroin, 06-monoacetylmorphine, and morphine in a lethal case following an oral heroin overdose.

A case of lethal overdose by heroin ingestion is presented. The concentrations of drugs were measured several hours after death. Heroin, 06-monoacetylmorphine, and morphine were identified and quantitated in blood, urine, and gastrointestinal contents by gas chromatography-mass spectrometry and high-performance liquid chromatography. Concentrations of heroin, 06-monoacetylmorphine, and morphine...

Postmortem Redistribution of the Heroin Metabolites Morphine and Morphine-3- Glucuronide in Rabbits over 24 hours

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A novel bivalent morphine/heroin vaccine that prevents relapse to heroin addiction in rodents.

Both pre-clinical and clinical studies make feasible the use of vaccines as novel therapeutic medications to treat drug addiction. No reports to date have shown the development of structural models of opiate candidate vaccines for treating human addiction to such compounds. Here we report on the initial development of a novel structural formulation of a bi-valent vaccine against morphine/heroin...